MDPennyPlayer
8 hours ago
Outstanding shares increased.
SHMN ? Pink Current
🔑 AS:3.00B ? OS:1.91B ? R:639.29M ? UR:1.27B ? DTC:1.26B
✨ Outstanding Shares Updated:
- 🔴 From: 1,600,576,407 (1.60B)
- 🟢 To: 1,910,576,407 (1.91B - 6/18/2024)
(Diff: 310.00M, % Change: 19.368%)
hardlesson
22 hours ago
He has now moved on to QuidelOrtho. He apparently fulfilled his tasks for Sohm, but according to his LinkedIn, he has been doing double duty for them since March 2023, and he left Sohm as of this month. He's always been an Independent guy, probably makes good money as a contractor/consultant.
Sad to see him go, but I appreciate your balanced comments. Hoping everyone still involved has learned a thing or two from him that can be continued, and if he needs replaced, they do it soon. According to their Tweet, they are still building their team, so maybe Aguilar already is in the middle of that process. Maybe we'll see an announcement at some point.
https://www.linkedin.com/in/wm-dewey-rushing-7505a95/
https://www.linkedin.com/company/quidelortho/
HL. Upsart Biotech at .0011.
SLC-JD
7 days ago
This is an excellent example of how a coherent media strategy can drive interest and volume, if not necessarily PPS (at least, not immediately).
Given that this ticker frequently goes days at a time with no to nominal shares traded, a "significant" bump in share price from a $100 trade is meaningless when there is no follow-up...nobody can capitalize on it. IMHO, we need volume first, PPS second. Putting out good news without bullshit revenue projections that the market immediately discounts goes a long way toward that goal.
Bravo, SHMN. Bravo.
Myth
1 week ago
SOHM, Inc. Announces its ABBIE Genome Editing Technology Successfully Engineered a T-cell immunotherapy from a Healthy Human Donor
CHINO HILLS, CA / ACCESSWIRE / June 10, 2024 / SOHM, Inc. (OTC PINK:SHMN) (the "Company"), a pharmaceutical and upstart biotechnology company that manufactures and markets generic drugs covering numerous treatment categories, announced that preliminary data from a 3rd party user resulted in ABBIE genome editing technology successfully engineering a T-cell from a healthy human donor and killed lung cancer cells in an experimental cancer model. The data was presented at the 2024 AACR conference in San Diego. This type of engineered T -Cell is called CAR-T (Chimeric Antigen Receptor T-Cell). This breakthrough method for immunotherapy against cancer is normally made using a virus-based delivery system. However, the ABBIE system can be delivered as an mRNA or purified protein along with donor polynucleic acid and guide RNA without the use of virus and is able to engineer lung cancer cell killing CAR T-cells very efficiently. "The preliminary data is intriguing and suggests ABBIE can be used as a powerful tool in the development of immunotherapies."-David Aguilar Ph.D. COO SOHM Inc.
Dr. Aguilar, further stated that, CAR T-cell therapy is a groundbreaking form of cancer treatment that harnesses the power of a patient's own immune system to target and destroy cancer cells. Chimeric antigen receptor (CAR) T-cells are engineered patient immune cells that are designed to recognize and attack specific proteins on the surface of cancer cells.
The importance of CAR T-cell therapy lies in its ability to provide targeted and personalized treatment for patients with certain types of cancer, particularly those that have not responded to traditional forms of treatment such as chemotherapy or radiation therapy. By reprogramming a patient's own immune cells to specifically target cancer cells, CAR T-cell therapy offers the potential for more effective and less toxic treatment options.
The field of CAR T-cell therapy has seen significant growth and advancement in recent years, with several CAR T-cell therapies receiving approval from regulatory agencies for the treatment of certain types of blood cancers, such as leukemia and lymphoma. These approvals have paved the way for further research and development in the field, leading to the exploration of CAR T-cell therapy for other types of cancer.
In addition to its potential to revolutionize cancer treatment, CAR T-cell therapy also holds promise for the treatment of other diseases, such as autoimmune disorders, neurological disease and infectious diseases. As researchers continue to refine and optimize CAR T-cell therapy, the field is expected to continue to grow and expand, offering new hope for patients battling cancer and other serious illnesses.
On average, CAR T-cell therapy can cost anywhere from $373,000 to $475,000 per patient in the United States. This high cost is primarily due to the complex and personalized nature of CAR T-cell therapy, which involves the extraction, modification, and re-infusion of a patient's own immune cells.
In terms of the market value for CAR T companies, According to Vision Research Reports, the global cancer immunotherapy market size was estimated at USD 125.73 billion in 2023 and it is projected to increase USD 280.11 billion by 2033 with a CAGR of 8.34% from 2024 to 2033. Some of the key players in the CAR T-cell therapy market include Novartis, Gilead Sciences (through its acquisition of Kite Pharma), and Bristol Myers Squibb (through its acquisition of Celgene).
Overall, the market value for CAR T companies is expected to continue to grow as more research and development efforts are focused on advancing CAR T-cell therapy and expanding its application to a wider range of cancer types and other diseases. The high cost of CAR T-cell therapy presents challenges in terms of access and affordability, but ongoing efforts are being made to address these issues and make this innovative treatment more widely available to patients in need. More effective production methods via use of techniques like ABBIE genome editing will assist in bringing patient costs down and expanding use of the therapy to many more people affected by cancers.
We are proud to announce ongoing work on ABBIE (A Binding Based Integrase Enzyme), a revolutionary retroviral integrase with a linked dCas9 DNA binding domain. ABBIE has the potential to revolutionize genome editing by allowing precise and targeted integration of predesigned donor DNA into the genome of cells. This groundbreaking technology opens up new possibilities for treating genetic diseases, developing novel therapies, and advancing scientific research. With its advanced targeting system, simplified operational protocols, and reduced risk of off-target effects, ABBIE could well become the gold standard for genetic modifications, paving the way for new discoveries and treatments said David Aguilar, COO of SOHM, Inc.
For more information about SOHM Inc. and its work on ABBIE, please visit www.SOHM.com
https://www.accesswire.com/873681/sohm-inc-announces-its-abbie-genome-editing-technology-successfully-engineered-a-t-cell-immunotherapy-from-a-healthy-human-donor
Myth
2 weeks ago
always with the negative spin, yes, most of us know that the 4th qtr comes out with the annual due 3/31.
here's an alternative spin if you will, they most likely are making kits as we speak, imo all they need to do is announce orders booked in q3, along with shipping lets say at least a million in rev, booked in q3. personally I would expect much more but not fully knowing the cost of the kits we would all be guessing.
Then we have the Licensing deals that could hit at any time, along with this..
The company has other types of kits and related products in development.
https://www.globenewswire.com/news-release/2024/05/22/2886768/0/en/SOHM-Inc-Targets-Revolutionary-New-ABBIE-Genome-Editing-Kits-for-Q3-2024.html
so bash away....
MDPennyPlayer
2 weeks ago
If what they say is true, Q3 starts in less than a month. They'd have to make these kits in some kind of quantity, market them, and get them shipped out. So realistically, it would be Q4 before they'd hit the financials, which puts all the way until April.
Maybe one of their two manufacturing facilities can produce something more than dust. The San Diego one has been getting ramped up for over a year now.
Myth
2 weeks ago
from the first announcement of the acquisition of ABBIE...
Revenue generations can be obtained immediately through licensing and gene-editing kits slated to be released for commercialization in 3Q/4Q 2024
https://www.globenewswire.com/en/news-release/2023/09/26/2749662/0/en/SOHM-Announces-Its-Acquisition-of-ABBIE-a-World-Class-Gene-Editing-Platform-Which-Can-Deliver-Genetic-Payloads-Using-Non-Viral-Vectors.html
the last PR ON 5/22/2024
SOHM, Inc., Targets Revolutionary New ABBIE Genome Editing Kits for Q3, 2024
https://www.globenewswire.com/news-release/2024/05/22/2886768/0/en/SOHM-Inc-Targets-Revolutionary-New-ABBIE-Genome-Editing-Kits-for-Q3-2024.html
Not sure what Dec 15th has to do with anything, maybe you can clarify...
Now that the A-Hole Barron has quietly PUNTED all the way to Dec 15th!
this is also confusing, 1000's of kits when Q2 fins are disclosed ?
(When Q-2: Fins are disclosed)
1000's of Kits & $M's will be mostly HOT AIR!
ChartTRACKER
4 weeks ago
$SHMN: MDP: You're proving to be an Invaluable "Proof-Reader"...
Thanks for bringing this to our attention.
This is GREAT NEWS!
It shows that there's a Probability of using other types of Gene Editing Tech [Using an Enzyme is ONE type...they are others]
So the USAGE of the word "Editor", implies that they've BROADENED the SCOPE, as some Nucleases may/may NOT be referred to as Enzymes [all this assuming that Barry didn't Copy n' Paste from somewhere...If so...further proof that a Soap-Seller can't be an Advanced Bio-Tech CEO]
ABBIE is "Binding BASED", as are all 👇️THREE Current Technologies in R&D
*********************************************************************************************************************
👇️Reference:- Genome-Editing Technologies: Principles
and Applications
Thomas Gaj,1,4 Shannon J. Sirk,2 Sai-lan Shui,3 and Jia Liu3,4
Here we review three foundational technologies—clustered regularly interspaced
short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs).
**************************************************************************************************************************
Myth
4 weeks ago
Q3 starts on July 1......
this could be a moonshot, posters can scoff all they want, my belief in ABBIE is unwavering, and has been since SHMN acquired it.
The revolutionary new ABBIE system is due to be sold as off-the-shelf kits in Q3. This has been possible due to our committed, consistent and focused approach by our lead scientists at our lab at UACI in Tucson, AZ.